巯基氧化酶2抗体
规格：1mg/1ml
英文名： QSOX2
别名： DKFZp762A2013; Neuroblastoma-derived sulfhydryl oxidase; QSCN6L1; QSOX2; QSOX2_HUMAN; Quiescin Q6 like 1; Quiescin Q6 sulfhydryl oxidase 2; Quiescin Q6-like protein 1; SOXN; Sulfhydryl oxidase 2.
分子量： 76kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human QSOX2
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜 分泌型蛋白
巯基氧化酶2抗体产品介绍：background: QSOX2 is a member of the sulfhydryl oxidase/quiescin-6 (Q6) family (QSOX1; MIM 603120) that regulates the sensitization of neuroblastoma cells for IFN-gamma (IFNG; MIM 147570)-induced cell death (Wittke et al., 2003 [PubMed 14633699]).[supplied by OMIM, Jun 2009] Function: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. Also seems to play a role in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis. Subcellular Location: Membrane. 巯基氧化酶2抗体Secreted. Cell membrane. Nucleus membrane. Seems to be predominantly targeted to the nuclear and outer plasma membrane. Tissue Specificity: Expressed in pancreas, brain, placenta, kidney, heart and fetal tissues. Weakly expressed in lung, liver and skeletal muscles. Similarity: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family. Contains 1 ERV/ALR sulfhydryl oxidase domain. Contains 1 thioredoxin domain. Gene ID:巯基氧化酶2抗体 169714 Database links: Entrez Gene: 788063 Cow Entrez Gene: 607571 Dog Entrez Gene: 101144374 Gorilla Entrez Gene: 169714 Human Entrez Gene: 227638 Mouse Entrez Gene: 100020838 Opossum Entrez Gene: 681023 Rat Omim: 612860 Human SwissProt: Q6ZRP7 Human SwissProt: Q3TMX7 Mouse Unigene: 657864 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
巯基氧化酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit