SFMBT1蛋白抗体
规格:1mg/1ml
英文名: SFMBT1
别名: DKFZp434L243; MGC93349; OTTMUSP00000030378; OTTMUSP00000030379; OTTMUSP00000030381; Renal ubiquitous protein 1; RU1; Scm like with four mbt domains 1; Scm like with four MBT domains protein 1; Scm rel
分子量: 98kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SFMBT1
交叉反应:Human, Mouse, Rat,
SFMBT1蛋白抗体细胞定位:细胞核
产品介绍:background: This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition. [provided by RefSeq, Jun 2012] Function: Histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription. Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of SFMBT1蛋白抗体associated corepressors and silencing of MYOD1 target genes. Part of the SLC complex in germ cells, where it may play a role during spermatogenesis. Tissue Specificity: Expressed in all cell lines and normal tissues tested, including the thymus. Similarity: Contains 4 MBT repeats. Contains 1 SAM (sterile alpha motif) domain. Gene ID: 51460 Database links: Entrez Gene: 51460 Human Entrez Gene: 54650 Mouse Entrez Gene: 58967 Rat Omim: 607319 Human SwissProt: Q9UHJ3 Human SwissProt: Q9JMD1 Mouse SwissProt: Q9JMD2 Rat Unigene: 343679 SFMBT1蛋白抗体Human Unigene: 294662 Mouse Unigene: 14839 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产SFMBT1蛋白抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid