肌浆/内质网钙ATP酶3抗体
规格：1mg/1ml
英文名： SERCA3
别名： Adenosine triphosphatase calcium; AT2A3_HUMAN; Atp2a3; ATPase Ca(2+) transporting ubiquitous; ATPase Ca++ transporting ubiquitous; Calcium pump 3; Calcium translocating P type ATPase; Sarco/endoplasmi
分子量： 114kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SERCA3
交叉反应：Human, Mouse, Chicken, Cow, Xenopus laevis, Xenopus tropicalis
细胞定位：细胞核
肌浆/内质网钙ATP酶3抗体产品介绍：background: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. Subcellular Location: Nucleus membrane. Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane. Tissue Specificity: Found in most tissues肌浆/内质网钙ATP酶3抗体. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues. Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. Database links: Entrez Gene: 395707 Chicken Entrez Gene: 512313 Cow Entrez Gene: 489 Human Entrez Gene: 53313 Mouse Entrez Gene: 肌浆/内质网钙ATP酶3抗体25391 Rat Entrez Gene: 495440 Xenopus laevis Entrez Gene: 779786 Xenopus tropicalis Omim: 601929 Human SwissProt: Q9YGL9 Chicken SwissProt: Q93084 Human SwissProt: Q64518 Mouse SwissProt: P18596 Rat Unigene: 513870 Human Unigene: 6306 Mouse Unigene: 9920 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产肌浆/内质网钙ATP酶3抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid