核孔蛋白样蛋白1抗体
规格:1mg/1ml
英文名: NUPL1
别名: KIAA0410; Nucleoporin like 1; Nucleoporin p58/p45; NUPL 1; OTTHUMP00000018146; OTTHUMP00000042323; PRO2463.
分子量: 59kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NUPL1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Cat,
细胞定位:细胞核
核孔蛋白样蛋白1抗体产品介绍:background: This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Function: Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Subunit: Component of the p62 complex, a complex at least composed of NUP62,核孔蛋白样蛋白1抗体 NUP54, and NUPL1. Interacts with NUTF2. Interacts with SRP1-alpha and Importin p97 proteins when they are together, but not with SRP1-alpha protein alone (By similarity). Subcellular Location: Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note: Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the transporter. Gene ID: 9818 Database links: Entrez Gene: 9818 Human Entrez Gene: 71844 Mouse Entrez Gene: 核孔蛋白样蛋白1抗体245922 Rat Omim: 607615 Human SwissProt: Q9BVL2 Human SwissProt: Q8R332 Mouse SwissProt: P70581 Rat Unigene: 507537 Human Unigene: 258051 Mouse Unigene: 11099 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用:核孔蛋白样蛋白1抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:染色质和核信号 信号转导 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid