胞质5',3'核苷酸抗体
规格:1mg/1ml
英文名: NT5C/dNT1
别名: 3''-pyrimidine nucleotidase; 5' nucleotidase, deoxy (pyrimidine); 5' nucleotidase, deoxy (pyrimidine), cytosolic type C; 5''(3'')-deoxyribonucleotidase; 5'(3')-deoxyribonucleotidase, cytosolic type; 5
分子量: 13kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NT5C/dNT
交叉反应:Human,
细胞定位:细胞浆
胞质5',3'核苷酸抗体产品介绍:background: This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011] Function: Dephosphorylates the 5'胞质5',3'核苷酸抗体 and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP. Subcellular Location: Cytoplasm. Tissue Specificity: Detected in skeletal muscle, heart胞质5',3'核苷酸抗体 and pancreas. Similarity: Belongs to the 5'(3')-deoxyribonucleotidase family. Database links: Entrez Gene: 30833 Human Omim: 191720 Human SwissProt: Q8TCD5 Human Unigene: 67201 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胞质5',3'核苷酸抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid