26S蛋白酶体非ATP酶调节亚基13抗体
规格：1mg/1ml
英文名： PSMD13
别名： 26S proteasome non ATPase regulatory subunit 13; 26S proteasome non-ATPase regulatory subunit 13; 26S proteasome regulatory subunit p40.5; 26S proteasome regulatory subunit RPN9; 26S proteasome regula
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PSMD13
交叉反应：Human, Cow,
细胞定位：细胞核 细胞浆
26S蛋白酶体非ATP酶调节亚基13抗体产品介绍：background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase26S蛋白酶体非ATP酶调节亚基13抗体 subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Function: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Subunit: Component of the PA700 complex. Similarity: Belongs to the proteasome subunit S11 family. Contains 1 PCI domain. Gene ID: 26S蛋白酶体非ATP酶调节亚基13抗体5719 Database links: Entrez Gene: 5719 Human Entrez Gene: 450913 Chimpanzee Entrez Gene: 513525 Cow Entrez Gene: 447560 Xenopus laevis Entrez Gene: 447992 Xenopus tropicalis Omim: 603481 Human SwissProt: Q5E964 Cow SwissProt: Q9UNM6 Human Unigene: 134688 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
26S蛋白酶体非ATP酶调节亚基13抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid