9号染色体开放阅
规格：1mg/1ml
英文名： Prune homolog 2/C9orf56
别名： A214N16 3; BCH motif containing molecule at the carboxyl terminal region 1; BMCC1; BNIP2 motif containing molecule at the carboxyl terminal region 1; BNIPXL; C9orf65; chromosome 9 open reading frame 6
分子量： 299kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Prune ho
交叉反应：Human, Mouse, Rat, Cow,
9号染色体开放阅细胞定位：细胞核 细胞浆
产品介绍：background: There are 2 named isoforms produced by alternative splicing. Function: Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1. Subunit: Homooligomer. Able to homodimerize via its C-terminal domain. Interacts with NME1. Interacts with GSK3; at focal adhesion complexes where paxillin and vinculin are colocalized. Subcellular Location: Cytoplasm. Nucleus. Cell junction ?focal adhesion Tissue 9号染色体开放阅Specificity: Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas. Similarity: Belongs to the PPase class C family. 9号染色体开放阅Prune subfamily. Database links: Entrez Gene: 158471 Human Entrez Gene: 353211 Mouse SwissProt: Q8WUY3 Human SwissProt: Q9D217 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
9号染色体开放阅产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞凋亡
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid