mRNA前体剪接因子Prp38抗体
规格:1mg/1ml
英文名: PRPF38A
别名: 2410002M20Rik; FLJ14936; MGC3320; OTTMUSP00000008592; PR38A_HUMAN; Pre mRNA splicing factor 38A; Pre-mRNA-splicing factor 38A; Prp38; PRP38 pre mRNA processing factor 38 (yeast) domain containing A; P
分子量: 37kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PRPF38A
交叉反应:Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
细胞定位:细胞核
mRNA前体剪接因子Prp38抗体产品介绍:background: HPRP18 is a 342 amino acid protein that localizes to nuclear speckles and plays a role in the second step of pre-mRNA splicing. A member of the PRP18 family, PRPF18 contains seven WD repeats and exists as two alternatively spliced isoforms which are encoded by a gene located on human chromosome 10p13. Chromosome 10 contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10. Function: May be required for pre-mRNA splicing. Subcellular Location: Nucleus. Similarity: Belongs to the PRP38 family.mRNA前体剪接因子Prp38抗体 Database links: Entrez Gene: 101091130 Cat Entrez Gene: 456858 Chimpanzee Entrez Gene: 507240 Cow Entrez Gene: 475350 Dog Entrez Gene: 101137881 Gorilla Entrez Gene: 100050749 Horse Entrez Gene: 84950 Human Entrez Gene: 230596 Mouse Entrez Gene: 100171974 Orangutan Entrez Gene: 100520571 Pig Entrez Gene: 100356051 Rabbit Entrez Gene: 101115326 Sheep Entrez Gene: 432312 mRNA前体剪接因子Prp38抗体Xenopus laevis Entrez Gene: 549894 Xenopus tropicalis SwissProt: Q0P5I6 Cow SwissProt: Q8NAV1 Human SwissProt: Q4FK66 Mouse SwissProt: Q5RDD2 Orangutan SwissProt: Q4FZQ6 Xenopus laevis SwissProt: Q28H87 Xenopus tropicalis Unigene: 5301 Human Unigene: 157534 Mouse Unigene: 413915 Mouse Unigene: 54468 Xenopus laevis Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用:mRNA前体剪接因子Prp38抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid