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产品名称: 组蛋白去乙?;父春涎腔鵖AP18抗体
产品型号: SAP18
产品展商: 单克隆抗体/多克隆抗体
产品文档: 无相关文档
简单介绍
组蛋白去乙?;父春涎腔鵖AP18抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。组蛋白去乙?;父春涎腔鵖AP18抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。
组蛋白去乙?;父春涎腔鵖AP18抗体
的详细介绍
组蛋白去乙?;父春涎腔鵖AP18抗体
规格:1mg/1ml
英文名: SAP18
别名: 18 kDa Sin3-associated polypeptide; 2HOR0202; Cell growth-inhibiting gene 38 protein; Histone deacetylase complex subunit SAP18; SAP18; SAP18_HUMAN; Sin3-associated polypeptide p18.
分子量: 17kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SAP18
交叉反应:Human, Mouse, Cow,
细胞定位:细胞核 细胞浆
组蛋白去乙?;父春涎腔鵖AP18抗体产品介绍:Function: Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Subunit: Found in a mRNA splicing-dependent exon junction complex (EJC). Component of the heterotrimeric ASAP (apoptosis- and splicing-associated protein) and PSAP complexes 组蛋白去乙?;父春涎腔鵖AP18抗体consisting of RNPS1, SAP18 and either ACIN1 or PNN, respectively; the ASAP and PSAP complexes probably are formed mutually exclusive. For the ASAP complex, the association of SAP18 seems to require a preformed RNPS1:ACIN1 complex. Forms a complex with SIN3A and HDAC1. Interacts with SUFU. Subcellular Location: Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm组蛋白去乙?;父春涎腔鵖AP18抗体. Tissue Specificity: Ubiquitous. Similarity: Belongs to the SAP18 family. Gene ID: 10284 Database links: Entrez Gene: 10284 Human Entrez Gene: 615692 Cow Entrez Gene: 20220 Mouse Entrez Gene: 290284 Rat Entrez Gene: 393693 Zebrafish Omim: 602949 Human SwissProt: Q3T022 Cow SwissProt: O00422 Human SwissProt: O55128 Mouse Unigene: 524899 Human Unigene: 30173 Mouse Unigene: 344671 Mouse Unigene: 74373 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
组蛋白去乙?;父春涎腔鵖AP18抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid