**珠蛋白抗体
规格：1mg/1ml
英文名： Uteroglobin
别名： blastokinin; CC10; CC16; CCPBP; CCSP; Clara cell phospholipid binding protein; Clara cell phospholipid-binding protein; clara cell secretory protein; Clara cell specific 10 kD protein; Clara Cells 10
分子量： 8kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse Uteroglo
交叉反应：Mouse, Rat,
细胞定位：分泌型蛋白
**珠蛋白抗体产品介绍：background: Uteroglobin belongs to the family of secretoglobins and is a secreted protein product of nonciliated bronchiolar Clara cells. There is convincing data suggesting it has phospholipase A2 inhibitory activity, as well as, a number of other immunomodulatory features including inhibition of interferon gamma signalling and Th1 vs. Th2 lymphocyte regulation. It was proposed as a potential peripheral marker of respiratory epithelial injury and bronchial dysfunction. Clara Cell Protein 16 concentrations have been determined in both serum and bronchoalveolar lavage fluid in numerous studies since 1994. In serum, its increase is associated with age, asbestos, nitrogen chloride and ozone exposure, sarcoidosis and high PEEP ventilation. Decreased serum CC16 levels are found after pulmonary resection, in silica-exposed workers, smokers and in asthma. Decreased CC16 concentrations were also found in the amniotic fluid of fetuses suffering from pulmonary hypoplasia caused by various mechanisms (diaphragmatic hernia, diabetic fetopathy, Turner and Down syndrome). In pleural effusions, the CC16 concentration **珠蛋白抗体appears to be associated with its diffusion from the lung as evidenced by high CC16 levels in cardiac pleural congestion. Function: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. Subunit: Homodimer; antiparallel disulfide-linked. Subcellular Location: Secreted. Tissue Specificity: Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways). Similarity: Belongs to the secretoglobin family. Gene ID: 7356 Database links: Entrez Gene: 7356 Human Entrez Gene: 22287**珠蛋白抗体 Mouse Entrez Gene: 25575 Rat Omim: 192020 Human SwissProt: P11684 Human SwissProt: Q06318 Mouse SwissProt: P17559 Rat Unigene: 523732 Human Unigene: 2258 Mouse Unigene: 2206 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. **珠蛋白(uteroglobin)是一**珠蛋白抗体种类固醇诱导的类似细胞因子的多功能蛋白质，具有**和**调节特性,它不仅在**内表达,而且可以在甲状腺,呼吸道,消化道，乳腺、胰腺、前列腺、脑垂体、睾丸等都有不同的表达。
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid