核仁蛋白9抗体
规格：1mg/1ml
英文名： NOL9
别名： FLJ23323; MGC131821; MGC138483; NET6; NOL9; Nucleolar protein 9.
分子量： 79kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NOL9
交叉反应：Human, Mouse, Rat, Cow,
细胞定位：细胞核
核仁蛋白9抗体产品介绍：background: NOL9 is a 702 amino acid protein that resides within the nucleolus. The gene encoding NOL9 maps to human chromosome 1, which spans about 260 million base pairs, making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes, there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When 核仁蛋白9抗体defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. Function: Polynucleotide 5'-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, 核仁蛋白9抗体has both DNA and RNA 5'-kinase activities. Probably binds RNA. Subunit: Interacts with PELP1, WDR18 and SENP3. Subcellular Location: Nucleus; nucleolus Similarity: Belongs to the Clp1 family. NOL9/GRC3 subfamily. Database links: Entrez Gene: 79707 Human SwissProt: Q5SY16 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核仁蛋白9抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 染色质和核信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid