NIPSNAP1蛋白抗体
规格：1mg/1ml
英文名： NIPSNAP1
别名： NIPSNAP 1; Nipsnap homolog 1 (C. elegans); Protein NipSnap homolog 1.
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NIPSNAP1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Zebrafish,
细胞定位：细胞膜
NIPSNAP1蛋白抗体产品介绍：background: This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011] Function: NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have NIPSNAP1蛋白抗体indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory. Subcellular Location: Mitochondrial Database links:NIPSNAP1蛋白抗体 Entrez Gene: 8508 Human Entrez Gene: 18082 Mouse Entrez Gene: 360971 Rat Omim: 603249 Human SwissProt: Q9BPW8 Human SwissProt: O55125 Mouse Unigene: 173878 Human Unigene: 293716 Mouse Unigene: 103205 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NIPSNAP1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid