核因子κB抑制蛋白样蛋白1抗体
规格:1mg/1ml
英文名: NFKBIL1
别名: I-kappa-B-like protein; IkappaBL; IKBL; IKBL1_HUMAN; Inhibitor of kappa B-like protein; LST1; NF-kappa-B inhibitor-like protein 1; NFKBIL; Nfkbil1; Nuclear factor of kappa light polypeptide gene enhan
分子量: 43kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NFKBIL1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat,
细胞定位:细胞核 细胞浆
核因子κB抑制蛋白样蛋白1抗体产品介绍:background: This gene encodes a divergent member of the I-kappa-B family of proteins. Its function has not been determined. The gene lies within the major histocompatibility complex (MHC) class I region on chromosome 6. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009] Function: May be a negative regulator of NF-kappa-B activation. Tissue Specificity: Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes. DISEASE: Defects in NFKBIL1 are a cause of susceptibility to rheumatoid arthritis (RA) [MIM:180300]. It is a systemic inflammatory核因子κB抑制蛋白样蛋白1抗体 disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Similarity: Contains 2 ANK repeats. Database links: Entrez Gene: 核因子κB抑制蛋白样蛋白1抗体4795 Human Entrez Gene: 18038 Mouse Entrez Gene: 361794 Rat Omim: 601022 Human SwissProt: Q9UBC1 Human SwissProt: O88995 Mouse SwissProt: Q8R2H1 Rat Unigene: 2764 Human Unigene: 300795 Mouse Unigene: 38632 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核因子κB抑制蛋白样蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid