锌指及同源结构域蛋白1抗体
规格:1mg/1ml
英文名: ZHX1
别名: ZHX 1; ZHX1; ZHX1_HUMAN; Zinc finger and homeodomain protein 1; Zinc fingers and homeobox 1; Zinc fingers and homeoboxes 1; Zinc fingers and homeoboxes protein 1.
分子量: 98kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZHX1
交叉反应:Human, Mouse, Rat, Cow, Horse, Sheep,
细胞定位:细胞核
锌指及同源结构域蛋白1抗体产品介绍:background: The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene. [provided by锌指及同源结构域蛋白1抗体 RefSeq, Feb 2011] Function: Acts as a transcriptional repressor. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitously expressed. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the ZHX family. Contains 2 C2H2-type zinc fingers. Contains 5 homeobox DNA-binding domains. Gene ID: 11244 Database links: Entrez Gene:锌指及同源结构域蛋白1抗体 11244 Human Entrez Gene: 420347 Chicken Entrez Gene: 22770 Mouse Entrez Gene: 171159 Rat Omim: 604764 Human SwissProt: Q9UKY1 Human SwissProt: P70121 Mouse SwissProt: Q8R515 Rat Unigene: 612084 Human Unigene: 244931 Mouse Unigene: 16902 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用:锌指及同源结构域蛋白1抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 转录调节因子 锌指蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid