TIP41样蛋白抗体
规格：1mg/1ml
英文名： TIPRL
别名： 1810011K17Rik; dJ69E11.3; MGC3794; Putative MAPK activating protein PM10; Putative MAPK-activating protein PM10; RP1-69E11.1; Tip; TIP41; TIP41-like protein; tiprl; TIPRL_HUMAN; TOR Signaling Pathway
分子量： 31kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TIPRL
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
细胞定位：细胞浆
TIP41样蛋白抗体产品介绍：Function: May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair. Subunit: Isoform 1 interacts with PPP2CA. Isoform 2 does notinteract with PPP2CA. Interacts with PPP2CB, PPP4C and PPP6C.Interacts with IGBP1; the interaction is dependent on PPP2CA.Associates with a protein phosphatase 2A PP2A(C):alpha-4 complex. Subcellular Location: Cytoplasm. Similarity: Belongs to the TIP41 family. TIP41样蛋白抗体Gene ID: 26172 Database links: Entrez Gene: 261726 Human Entrez Gene: 226591 Mouse Entrez Gene: TIP41样蛋白抗体360869 Rat Omim: 611807 Human SwissProt: O75663 Human SwissProt: Q8BH58 Mouse SwissProt: A2VCX1 Rat Unigene: 209431 Human Unigene: 21520 Mouse Unigene: 56867 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：TIP41样蛋白抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid