细胞迁移诱导蛋白19抗体
规格：1mg/1ml
英文名： NBR1
别名： 1A1 3B; 1A13B; Cell migration-inducing gene 19 protein; KIAA0049; M17S2; Membrane component chromosome 17 surface marker 2; Membrane component chromosome 17 surface marker 2; MIG 19; MIG19; Migration
分子量： 107kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NBR1
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
细胞迁移诱导蛋白19抗体产品介绍：background: The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014] Function: Acts probably细胞迁移诱导蛋白19抗体 as a receptor for selective autophagosomal degradation of ubiquitinated targets. Subcellular Location: Cytoplasm. Cytoplasmic vesicle; autophagosome. Lysosome. Cytoplasm; myofibril; sarcomere; M line. In cardiac muscles localizes to the sarcomeric M line (By similarity). Is targeted to lysosomes for degradation. Similarity: Contains 1 OPR domain. Contains 1 UBA domain. Contains 1 ZZ-type zinc细胞迁移诱导蛋白19抗体 finger. Gene ID: 4077 Database links: Entrez Gene: 4077 Human Entrez Gene: 17966 Mouse Entrez Gene: 303554 Rat Omim: 166945 Human SwissProt: Q14596 Human SwissProt: P97432 Mouse SwissProt: Q501R9 Rat Unigene: 277721 Human Unigene: 708158 Human Unigene: 784 Mouse Unigene: 94975 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产细胞迁移诱导蛋白19抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit