天冬氨酰tRNA连接酶2抗体
规格:1mg/1ml
英文名: NARS2
别名: AI875199; AsnRS; Asparagine tRNA ligase 2; Asparagine tRNA ligase 2 mitochondrial; Asparagine tRNA ligase; Asparaginyl tRNA synthetase 2; Asparaginyl tRNA synthetase 2 mitochondrial; FLJ23441; MGC1251
分子量: 52kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NARS2
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:
天冬氨酰tRNA连接酶2抗体产品介绍:background: SLM5 (mitochondrial asparaginyl-tRNA synthetase, Asparagine-tRNA ligase) is a mitochondrial protein encoded by the human gene NARS2. AsnRS belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl tRNA synthetases (aaRS) are enzymes that catalyze the esterification of a specific amino acid or its precursor to its compatible cognate tRNA to form an aminoacyl-tRNA. The synthetase first binds ATP and the corresponding amino acid or its precursor to form an aminoacyl-adenylate and release inorganic pyrophosphate (PPi). The adenylate-aaRS complex then binds the appropriate tRNA molecule, and the amino acid is transferred from the 天冬氨酰tRNA连接酶2抗体aa-AMP to either the 2'- or 3'-OH of the last tRNA base (A76) at the 3'-end. Some synthetases also mediate a proofreading reaction to ensure high fidelity of tRNA charging; if the tRNA is found to be improperly charged, the aminoacyl-tRNA bond is hydrolyzed天冬氨酰tRNA连接酶2抗体. SLM5 acts to attach asparagine residues to its cognate tRNA. Subcellular Location: Mitochondrion matrix. Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Gene ID: 79731 Database links: Entrez Gene: 79731 Human SwissProt: Q96I59 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
天冬氨酰tRNA连接酶2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid