NARFL蛋白抗体
规格：1mg/1ml
英文名： NARFL
别名： Cytosolic Fe-S cluster assembly factor NARFL; FLJ21988; HPRN; IOP1; Iron only hydrogenase like protein 1; iron-only hydrogenase-like protein 1; LET1 like/JFP15; LET1L; Nuclear prelamin A recognition f
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NARFL
交叉反应：Human, Mouse, Rat, Chicken, Dog,
细胞定位：细胞核 细胞浆
NARFL蛋白抗体产品介绍：background: NARFL (nuclear prelamin A recognition factor-like), also known as cytosolic Fe-S cluster assembly factor NARFL, HPRN, PRN (protein related to Narf), LET1L or IOP1 (iron-only hydrogenase-like protein 1), is a 476 amino acid protein belonging to the NARF family. Widely expressed, NARFL is required for extramitochondrial sulfur and iron protein maturation and may indirectly negatively regulate HIF-1?expression. Existing as three alternatively spliced isoforms, NARFL is encoded by a gene that maps to human chromosome 16p13.3 and murine chromosome 17 A3.3. Function: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, aNARFL蛋白抗体 multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect. Subcellular Location: Nuclear Cytosolic iron-sulfur protein assembly complex. Tissue Specificity: Widely expressed. Similarity: Belongs to the NARF family. Gene ID: 64428 Database links: Entrez Gene: NARFL蛋白抗体64428 Human Omim: 611118 Human SwissProt: Q9H6Q4 Human Unigene: 513247 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NARFL蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 新陈代谢
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid