平滑肌细胞相关蛋白4抗体
规格：1mg/1ml
英文名： MFSD1
别名： FLJ14153; Major facilitator superfamily domain containing 1; Major facilitator superfamily domain-containing protein 1; MFSD1; MFSD1_HUMAN; SMAP 4; SMAP-4; SMAP4; Smooth muscle cell-associated protein
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MFSD1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat,
细胞定位：细胞膜
平滑肌细胞相关蛋白4抗体产品介绍：background: MFSD1 is a 465 amino acid multi-pass membrane protein that exists as two isoforms as a result of alternative splicing events. A related protein, MFSD2, may play a role in placenta morphogenesis and may also be involved in adaptive thermogenesis. The gene encoding MFSD1 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. Function: May play a role in eye development. Subcellular Location: Membrane; Single-pass type II membrane protein Tissue Specificity: Specifically expressed in brain. Strongly expressed in medulla oblongata and to a lower extent in hippocampus and corpus callosum. Expressed in keratinocytes. DISEASE: Nanophthalmos 2 (NNO2) [MIM:609549]: Rare autosomal recessive disorder of eye development 平滑肌细胞相关蛋白4抗体characterized by extreme hyperopia and small functional eyes. Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.8 Microphthalmia, isolated, 5 (MCOP5) [MIM:611040]: A disorder characterized by posterior microphthalmia, retinitis pigmentosa, foveoschisis and optic disk drusen. Microphthalmia is a disorder of eye formation, ranging from small size of a single 平滑肌细胞相关蛋白4抗体eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, and other abnormalities may also be present. Note: The disease is caused by mutations affecting the gene represented in this entry. Similarity: Contains 2 CUB domains. Contains 1 FZ (frizzled) domain. Contains 2 LDL-receptor class A domains. Database links: Entrez Gene: 64747 Human Entrez Gene: 66868 Mouse Entrez Gene: 361957 Rat Entrez Gene: 641486 Zebrafish SwissProt: Q9H3U5 Human SwissProt: Q9DC37 Mouse SwissProt: Q32LQ6 Zebrafish Unigene: 58663 Human Unigene: 271975 Mouse Unigene: 391791 Rat Unigene: 121245 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
平滑肌细胞相关蛋白4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid