Rubicon蛋白抗体
规格：1mg/1ml
英文名： Rubicon
别名： SCAR15; RUBICON; Baron; Beclin 1 associated RUN domain containing protein; Beclin-1 associated RUN domain containing protein; hypothetical protein LOC9711; KIAA0226; OTTHUMP00000208021; OTTHUMP0000020
分子量： 106kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Rubicon
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Zebrafish, Guinea Pig, Cat,
细胞定位：
Rubicon蛋白抗体产品介绍：background: The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) Rubicon蛋白抗体binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014] DatabasRubicon蛋白抗体e links: Entrez Gene: 9711 Human Entrez Gene: 100502698 Mouse Omim: 613516 Human SwissProt: Q92622 Human SwissProt: Q80U62 Mouse Unigene: 478868 Human Unigene: 327319 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rubicon蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid