NOGO66受体相关蛋白2抗体
规格：1mg/1ml
英文名： NgR2/RTN4RL2
别名： NgR2; NGRH1; NGRL3; Nogo 66 receptor related protein 2; Nogo receptor-like 3; Nogo-66 receptor homolog 1; Nogo-66 receptor-related protein 2; R4RL2_HUMAN; Reticulon-4 receptor-like 2; RTN4RL2.
分子量： 46kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NgR2/RTN
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位：细胞膜
NOGO66受体相关蛋白2抗体产品介绍：background: NgR2 belongs to the Nogo receptor family and contains eight LRR (leucine-rich) repeats, one LRRNT domain and a single LRRCT domain. The gene encoding NgR2 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Function: May play a role in regulating axonal regeneration and plasticity in the ***** central nervous system. Subcellular Location: Cell membrane Tissue Specificity:NOGO66受体相关蛋白2抗体 Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid. Post-translational modifications: Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein. Similarity:NOGO66受体相关蛋白2抗体 Belongs to the Nogo receptor family. Contains 8 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Database links: Entrez Gene: 349667 Human Entrez Gene: 269295 Mouse Entrez Gene: 311169 Rat Omim: 610462 Human SwissProt: Q86UN3 Human SwissProt: Q7M6Z0 Mouse SwissProt: Q80WD1 Rat Unigene: 502618 Human Unigene: 389289 Mouse Unigene: 86447 Mouse Unigene: 162683 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NOGO66受体相关蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid