酸性核糖体磷蛋白大亚基P0抗体
规格:1mg/1ml
英文名: RPLP0
别名: 36B4; 60S acidic ribosomal protein P0; 60S ribosomal protein L10E; Acidic ribosomal phosphoprotein P0; Arbp; L10E; LP0; MGC107165; MGC107166; MGC111226; MGC88175; OTTMUSP00000015585; P0; PRLP0; Riboso
分子量: 34kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RPLP0
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:
酸性核糖体磷蛋白大亚基P0抗体产品介绍:background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene酸性核糖体磷蛋白大亚基P0抗体 dispersed through the genome. [provided by RefSeq, Jul 2008]. Function: Ribosomal protein P0 is the functional equivalent of E.coli protein L10. Subunit: P0 forms a pentameric complex by interaction with dimers of P1 and P2. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with Lassa virus Z protein. Interacts with APEX1. Subcellular Location: Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules 酸性核糖体磷蛋白大亚基P0抗体containing untranslated mRNAs. Similarity: Belongs to the ribosomal protein L10P family. Gene ID: 6175 Database links: Entrez Gene: 6175 Human Entrez Gene: 11837 Mouse Entrez Gene: 64205 Rat Omim: 180510 Human SwissProt: P05388 Human SwissProt: P14869 Mouse SwissProt: P19945 Rat Unigene: 546285 Human Unigene: 371545 Mouse Unigene: 5286 Mouse Unigene: 1079 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
酸性核糖体磷蛋白大亚基P0抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:染色质和核信号 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid