RSC1A1蛋白抗体
规格:1mg/1ml
英文名: RSC1A1
别名: RS1; Transporter regulator RS1.
分子量: 68kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RSC1A1
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
RSC1A1蛋白抗体产品介绍:background: RSC1A1 is 617 amino acid nuclear protein that localizes to the inner side of the plasma membrane and the Golgi apparatus. Expressed in small intestine, kidney and brain, RSC1A1 mediates transcriptional and post-transcriptional regulation of Na(+)-D-glucose cotransporter SGLT-1 (sodium/glucose cotransporter 1). RSC1A1 is thought to inhibit the dynamin-dependent release of SGLT-1-containing vesicles from the TGN (trans-Golgi network). Mutations in the gene encoding RSC1A1 may lead to leptin-independent up-regulation of food intake, which is suggested to be partially responsible for obesity. The gene encoding is RSC1A1 located on human chromosome 1RSC1A1蛋白抗体, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the humanRSC1A1蛋白抗体 genome. Subcellular Location: Cell Membrane, Golgi Apparatus and Nuclear. Database links: Entrez Gene: 6248 Human Omim: 601966 Human SwissProt: Q92681 Human Unigene: 657818 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RSC1A1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid