RRAGD蛋白抗体
规格:1mg/1ml
英文名: RRAGD
别名: bA11D8.2.1; DKFZp761H171; FLJ44176; OTTHUMP00000016853; Rag D; Rag D protein; RAGD; RagDRRAGD; Ras related GTP binding D; Ras-related GTP binding protein D; Ras-related GTP-binding protein D; RRAGD; R
分子量: 45kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RRAGD
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Cat,
细胞定位:细胞核 细胞浆
RRAGD蛋白抗体产品介绍:background: RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004] Function: Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Subcellular Location: Cytoplasm. Nucleus. Lysosome. Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus,RRAGD蛋白抗体 depending on the bound nucleotide state of associated RRAGA. Similarity: Belongs to the GTR/RAG RRAGD蛋白抗体GTP-binding protein family. Database links: Entrez Gene: 58528 Human Entrez Gene: 52187 Mouse Entrez Gene: 297960 Rat Omim: 608268 Human SwissProt: Q9NQL2 Human SwissProt: Q7TT45 Mouse Unigene: 31712 Human Unigene: 300814 Mouse Unigene: 396693 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RRAGD蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid