蛋白酪氨酸磷酸酶亩mu抗体
规格：1mg/1ml
英文名： PTP mu
别名： hR PTPu; Protein tyrosine phosphatase mu; Protein tyrosine phosphatase receptor type M; Protein tyrosine phosphatase receptor type mu polypeptide; Protein-tyrosine phosphatase mu; PTPRL1; Ptprm; PTPRM
分子量： 162kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PTP mu
交叉反应：Human, Mouse, Rat, Dog, Cow,
细胞定位：细胞膜
蛋白酪氨酸磷酸酶亩mu抗体产品介绍：background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008] 蛋白酪氨酸磷酸酶亩mu抗体Function: Involved in cell-cell adhesion through homophilic interactions. May play a key role in signal transduction and growth control. Subcellular Location: Membrane. Similarity: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily. Contains 4 fibronectin type-III domains. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 MAM domain. Contains 2 tyrosine-protein phosphatase蛋白酪氨酸磷酸酶亩mu抗体 domains. Gene ID: 5797 Database links: Entrez Gene: 5797 Human Entrez Gene: 536092 Cow Entrez Gene: 480203 Dog Entrez Gene: 19274 Mouse Entrez Gene: 100173948 Orangutan Entrez Gene: 29616 Rat Omim: 176888 Human SwissProt: P28827 Human SwissProt: P28828 Mouse Unigene: 49774 Human Unigene: 311809 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白酪氨酸磷酸酶亩mu抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid