Tat结合蛋白7抗体
规格：1mg/1ml
英文名： TBP7
别名： 26S protease regulatory subunit 6B; 26S proteasome AAA ATPase subunit RPT3; 26S proteasome AAA-ATPase subunit RPT3; MB67 interacting protein; MB67-interacting protein; MIP224; Protease 26S subunit 6;
分子量： 47kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TBP7
交叉反应：Human, Mouse, Rat, Dog, Horse, Cat,
细胞定位：细胞核 细胞浆
Tat结合蛋白7抗体产品介绍：background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively Tat结合蛋白7抗体spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] Function: The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. Subcellular Location: Cytoplasm. Nucleus. Similarity: Belongs to the AAA ATPase family. Gene ID: 5704 Database links: Entrez Gene: 5704 Human Entrez Gene: 737578 Chimpanzee Entrez Gene: 510029 Cow Entrez Gene: 23996 Mouse Entrez Gene: Tat结合蛋白7抗体100341658 Rabbit Entrez Gene: 117262 Rat Entrez Gene: 398853 Xenopus laevis Entrez Gene: 493372 Xenopus tropicalis Entrez Gene: 326884 Zebrafish Omim: 602707 Human SwissProt: Q3T030 Cow SwissProt: P43686 Human SwissProt: P54775 Mouse SwissProt: Q63570 Rat Unigene: 211594 Human Unigene: 29582 Mouse Unigene: 11341 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Tat结合蛋白7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid