p52核糖体蛋白S6激酶抗体
规格：1mg/1ml
英文名： RPS6KC1
别名： p52 S6 kinase; 52 kDa ribosomal protein S6 kinase; humS6PKh1; KS6C1_HUMAN; Ribosomal protein S6 kinase 52kD polypeptide 1; Ribosomal protein S6 kinase 52kDa polypeptide 1; Ribosomal protein S6 kinase
分子量： 119kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RPS6KC1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆 细胞膜
p52核糖体蛋白S6激酶抗体产品介绍：background: p52 S6 kinase, also known as RPS6KC1 (ribosomal protein S6 kinase, 52kDa, polypeptide 1) or RPK118, is a 1,066 amino acid member of the Ser/Thr kinase family that localizes to both the cytoplasm and the nucleus and contains one MIT domain, one PX domain and two protein kinase domains. Expressed at high levels in brain, placenta, heart, testis, kidney, liver and skeletal muscle, p52 S6 kinase catalyzes the ATP-dependent phosphorylation of target proteins and is thought to be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. Function: May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. Subcellular Location: Cytoplasm. Membrane. Also found in some small dot-like or ring-shaped early endosome structures.p52核糖体蛋白S6激酶抗体 Tissue Specificity: Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon. Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily. Contains 1 MIT domain. Contains 2 protein kinase domains. Contains 1 PX (phox homology) domain. Database links: Entrez Gene: 26750 Human Entrezp52核糖体蛋白S6激酶抗体 Gene: 320119 Mouse GenBank: NP_001129610.1 Human GenBank: NP_036556.2 Human SwissProt: Q96S38 Human SwissProt: Q8BLK9 Mouse Unigene: 591416 Human Unigene: 220912 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
p52核糖体蛋白S6激酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid