MEX3C蛋白抗体
规格:1mg/1ml
英文名: MEX3C
别名: BM 013; BM013; FLJ38871; Mex 3 homolog C C. elegans; Mex 3, C. elegans, homolog of C; MEX 3C; MEX3C; MEX3C_HUMAN; Ring finger and KH domain containing 2; RING finger and KH domain containing protein 2
分子量: 69kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MEX3C
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位:细胞核 细胞浆
MEX3C蛋白抗体产品介绍:background: This gene encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. The protein interacts with mRNA via the KH domains, and the protein shuttles between the nucleus and cytoplasm. Polymorphisms in this gene may contribute to hypertension. [provided by RefSeq, Oct 2009] Function: RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms. Subunit: Interacts with USP7, which antagonizes the ability to degrade mRNA. Subcellular Location: Cytoplasm. Nucleus. Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the MEX3C蛋白抗体nucleus through the CRM1 export pathway. Tissue Specificity: Highest levels found in fetal brain and testis. Also expressed in thymus, salivary gland and uterus. Week expression in the intestine. DISEASE: Note=Genetic variations in MEX3C may be associated with susceptibility to essential hypertension. Similarity: Contains 2 KH domains. Contains 1 RING-type zinc finger. Gene ID: 51320 Database links: Entrez Gene:MEX3C蛋白抗体 51320 Human Entrez Gene: 240396 Mouse Entrez Gene: 307271 Rat Omim: 611005 Human SwissProt: Q5U5Q3 Human SwissProt: Q05A36 Mouse Unigene: 465144 Human Unigene: 24131 Mouse Unigene: 436942 Mouse Unigene: 8138 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MEX3C蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 结合蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid