甲基样蛋白17抗体
规格:1mg/1ml
英文名: METTL17/METT11D1
别名: False p73 target gene protein; FLJ20859; Methyltransferase 11 domain containing 1; Methyltransferase 11 domain containing protein 1; Methyltransferase like protein 17 mitochondrial; METTL17; Protein R
分子量: 51kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human METTL17/
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Cat,
细胞定位:
甲基样蛋白17抗体产品介绍:background: METTL17 is a 456 amino acid mitochondrial protein that belongs to the Rsm22 family and methyltransferase superfamily. Existing as three alternatively spliced isoforms, METT11D1 is thought to function as a component of the mitochondrial small ribosomal subunit. The gene encoding METT11D1 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to 甲基样蛋白17抗体the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. Function: May be a component of the mitochondrial small ribosomal subunit. Similarity: Belongs to the methyltransferase superfamily. Rsm22 family. Database links: Entrez Gene: 64745 Human Entrez Gene: 52535 Mouse Entrez Gene: 305845 Rat SwissProt: Q9H7H0 Human SwissProt: Q3U2U7 Mouse Unigene:甲基样蛋白17抗体 512693 Human Unigene: 5750 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甲基样蛋白17抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 表观遗传学
储存条件: Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid