MED30蛋白抗体
规格:1mg/1ml
英文名: MED30
别名: TRAP25; MED30; MED30_HUMAN; Mediator complex subunit 30; Mediator of RNA polymerase II transcription subunit 30; THRAP6; Thyroid hormone receptor-associated protein 6; Thyroid hormone receptor-associa
分子量: 20kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MED30
交叉反应:Human, Mouse, Dog, Pig, Horse, Rabbit, Sheep,
MED30蛋白抗体细胞定位:细胞核
产品介绍:background: The multiprotein TRAP/Mediator complex facilitates gene expression through a wide variety of transcriptional activators. MED30 is a component of this complex that appears to be metazoan specific (Baek et al., 2002 [PubMed 11909976]).[supplied by OMIM, Nov 2010] Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold forv the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Subcellular Location: Nucleus. Tissue Specificity: Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. Similarity: Belongs to the MediatorMED30蛋白抗体 complex subunit 30 family. Gene ID: 90390 Database links: Entrez Gene: 90390 Human Entrez Gene: 69790 Mouse Entrez Gene: 299905 Rat Omim: 610237 Human SwissProt: Q96HR3 Human SwissProt: Q9CQI9 Mouse Unigene: 492612 Human Unigene: 195562 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MED30蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid