苹果酸脱氢酶1B抗&#
规格：1mg/1ml
英文名： MDH1B
别名： malate dehydrogenase 1B; malate dehydrogenase 1B NAD; Putative malate dehydrogenase 1B.
分子量： 59kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MDH1B
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
苹果酸脱氢酶1B抗&#产品介绍：background: MDH1B is a 518 amino acid protein that belongs to the MDH type 2 family and LDH/MDH superfamily. Existing as three alternatively spliced isoforms, the gene encoding MDH1B maps to human chromosome 2q33.3. Chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and 苹果酸脱氢酶1B抗&#vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. Function: MDH1B has been detected at the transcript level and is part of the 苹果酸脱氢酶1B抗&#malate dehydrogenase superfamily. Subcellular Location: Cytoplasmic Database links: Entrez Gene: 130752 Human SwissProt: Q5I0G3 Human Unigene: 147816 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产苹果酸脱氢酶1B抗&#品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 新陈代谢
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid