微小染色体维持缺陷蛋白9抗体
规格：1mg/1ml
英文名： MCM9
别名： C6orf61 ; DNA replication licensing factor MCM9 ; hMCM9 ; MCMDC1 ; Mini-chromosome maintenance deficient 9 ; Mini-chromosome maintenance deficient domain-containing protein 1.
分子量： 44, 127kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MCM9
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核
微小染色体维持缺陷蛋白9抗体产品介绍：background: The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1. [provided by RefSeq, Nov 2010] Function: Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to微小染色体维持缺陷蛋白9抗体 process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. Subunit: Component of the MCM8-MCM9 complex, which forms a hexamer composed of MCM8 and MCM9. Subcellular Location: Nucleus Similarity: Belongs to the MCM family. Contains 1 MCM domain. Database links: Entrez Gene: 254394 Human微小染色体维持缺陷蛋白9抗体 Entrez Gene: 361852 Rat Omim: 610098 Human SwissProt: Q9NXL9 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
微小染色体维持缺陷蛋白9抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid