腺苷蛋氨酸1抗体
规格：1mg/1ml
英文名： MAT1A
别名： AdoMet; AdoMet synthetase 1; AI046368; Ams; MAT; METK1_HUMAN; MAT I/III; MATA1; Methionine adenosyltransferase 1; Methionine adenosyltransferase I, alpha; Methionine adenosyltransferase I/III; MGC1085
分子量： 44kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MAT1A
交叉反应：Human, Mouse, Rat, Cow, Horse,
细胞定位：细胞浆
腺苷蛋氨酸1抗体产品介绍：background: MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. Mutations in this gene are associated with methionine adenosyltransferase deficiency. Function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. Subunit: Homotetramer (MAT-I) or homodimer (MAT-III). Tissue Specificity: Expressed in liver. Post-translational modifications: S-nitrosylation of Cys-120 inactivates the enzyme. DISEASE: Methionine adenosyltransferase deficiency (MATD) [MIM:250850]: An inborn error of metabolism resulting in isolated hypermethioninemia. Most patients腺苷蛋氨酸1抗体 have no clinical abnormalities, although some neurologic symptoms may be present in rare cases with severe loss of methionine adenosyltransferase activity. Note: The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs腺苷蛋氨酸1抗体 to the AdoMet synthase family. Gene ID: 610550 Database links: Entrez Gene: 610550 Human Entrez Gene: 11720 Mouse Entrez Gene: 25331 Rat Omim: 610550 Human SwissProt: Q00266 Human SwissProt: Q91X83 Mouse SwissProt: P13444 Rat Unigene: 282670 Human Unigene: 14064 Mouse Unigene: 10418 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
腺苷蛋氨酸1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid