磷酸化丝氨酸/苏氨酸蛋白激酶MARK3抗体
规格：1mg/1ml
英文名： MARK3
别名： C-TAK1; Cdc25C associated protein kinase 1; Cdc25C-associated protein kinase 1; CTAK1; ELKL motif kinase 2; EMK-2; Emk2; ETK 1; KIAA4230; KP78; MAP microtubule affinity regulating kinase 3; MAP/microt
分子量： 84kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MARK3
交叉反应：Human, Mouse, Rat, Pig, Cow,
细胞定位：细胞浆 细胞膜
磷酸化丝氨酸/苏氨酸蛋白激酶MARK3抗体产品介绍：background: The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] Function: Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Tissue Specificity:磷酸化丝氨酸/苏氨酸蛋白激酶MARK3抗体 Ubiquitous. Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily. Contains 1 KA1 (kinase-associated) domain. Contains 1 protein kinase domain. Contains 1 UBA domain. Gene ID:磷酸化丝氨酸/苏氨酸蛋白激酶MARK3抗体 4140 Database links: Entrez Gene: 4140 Human Entrez Gene: 17169 Mouse Entrez Gene: 170577 Rat Omim: 602678 Human SwissProt: P27448 Human SwissProt: Q03141 Mouse SwissProt: Q8VHF0 Rat Unigene: 35828 Human Unigene: 260504 Mouse Unigene: 408955 Mouse Unigene: 420865 Mouse Unigene: 23232 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化丝氨酸/苏氨酸蛋白激酶MARK3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid