**中心激酶样激酶抗体
规格：1mg/1ml
英文名： MAP4K3/GLK
别名： Germinal center kinase like kinase; Germinal center kinase-related protein kinase; GLK; MAPK/ERK kinase kinase kinase 3; MAPKKKK3; MEK kinase kinase 3; MEKKK 3; MEKKK3; mitogen-activated protein kinas
分子量： 101kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MAP4K3/G
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核 细胞浆
**中心激酶样激酶抗体产品介绍：background: This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] Function: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Subunit: Interacts with SH3GL2. Interaction appears to regulate MAP4K3-mediated JNK activation Subcellular Location: Cytoplasmic and Nuclear Tissue Specificity: Ubiquitously expressed in all tissues examined, with high **中心激酶样激酶抗体levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver. Similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. Contains 1 CNH domain. Contains 1 protein**中心激酶样激酶抗体 kinase domain. Database links: Entrez Gene: 8491 Human Entrez Gene: 225028 Mouse Entrez Gene: 170920 Rat Omim: 604921 Human SwissProt: Q8IVH8 Human SwissProt: Q99JP0 Mouse SwissProt: Q924I2 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
**中心激酶样激酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid