MAP3K12结合抑制蛋白1抗体
规格:1mg/1ml
英文名: MBIP/MAP3K12 binding inhibitory protein 1
别名: MAP3K12 binding inhibitory protein 1; MAP3K12-binding inhibitory protein 1; MAPK upstream kinase binding inhibitory protein; MAPK upstream kinase-binding inhibitory protein; MBIP; MBIP1_HUMAN; MUK bin
分子量: 39kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MBIP/MAP
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:细胞核 细胞浆
MAP3K12结合抑制蛋白1抗体产品介绍:Function: Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Subunit: Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5. Subcellular Location: Nucleus. Cytoplasm. Shows a cytoplasmicMAP3K12结合抑制蛋白1抗体 localization when coexpressed with MAP3K12. Tissue Specificity: UbiquitousMAP3K12结合抑制蛋白1抗体. High expression seen in the heart and lung. Gene ID: 51562 Database links: Entrez Gene: 51562 Human Entrez Gene: 217588 Mouse Entrez Gene: 362740 Rat Omim: 609431 Human SwissProt: Q9NS73 Human SwissProt: Q99LQ1 Mouse Unigene: 368647 Human Unigene: 25656 Mouse Unigene: 24202 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MAP3K12结合抑制蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid