镁转运蛋白1抗体
规格：1mg/1ml
英文名： MAGT1
别名： bA217H1; DKFZp564K142; FLJ14726; IAG2; IAP; Implantation-associated protein; Magnesium transporter 1; MagT1; MGC64926; MRX95; Oligosaccharyltransferase 3 homolog B; OST3B; OTTHUMP00000023589; OTTHUMP0
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MAGT1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
镁转运蛋白1抗体产品介绍：background: This gene encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29. [provided by RefSeq, Jan 2010] Function: May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg2+ transport in epithelial cells. Subunit: Weakly associates with the oligosaccharyl transferase (OST) complex which contains at least RPN1/ribophorin I, RPN2/ribophorin II, OST48, DAD1, and either 镁转运蛋白1抗体STT3A or STT3B Subcellular Location: Cell membrane. Tissue Specificity: Ubiquitous. Expressed at very low levels in brain, lung and kidney. DISEASE: Immunodeficiency, X-linked, with magnesium defect, Epstein-Barr virus infection and neoplasia (XMEN) [MIM:300853]: A disease characterized by CD4 lymphopenia, severe chronic viral infections, and defective T-lymphocyte activation. Note: The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the OST3/OST6 family. Contains 1 thioredoxin domain. Database links: Entrez 镁转运蛋白1抗体Gene: 84061 Human Entrez Gene: 67075 Mouse Entrez Gene: 116967 Rat Omim: 300715 Human SwissProt: Q9H0U3 Human SwissProt: Q9CQY5 Mouse SwissProt: O35777 Rat Unigene: 323562 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
镁转运蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid