降钙素基因相关肽1型受体抗体
规格：1mg/1ml
英文名： CRLR
别名： CGRPR; calcitonin receptor like precursor; Calcitonin gene related peptide type 1 receptor; Calcitonin receptor like; CALCRL; CGRP type 1 receptor; CGRPR; Calcitonin gene related peptide type 1 recept
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CGRPR1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
降钙素基因相关肽1型受体抗体产品介绍：background: CRLR is a receptor for calcitonin gene related peptide type 1. The activity of CRLR is mediated by G proteins which activate adenylyl cyclase. CRLR expression has been reported in brain, lung, blood vessel, liver, and intestinal tract. ESTs have been isolated from B Cell/lung/testis, bone marrow, embryo, lung, and synovium libraries. Function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Subunit: Heterodimer降钙素基因相关肽1型受体抗体 of CALCRL and RAMP1, RAMP2 or RAMP3. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Predominantly expressed in the lung and heart. Similarity: Belongs to the G-protein coupled receptor 2 family. Gene ID: 10203降钙素基因相关肽1型受体抗体 Database links: Entrez Gene: 10203 Human Entrez Gene: 54598 Mouse Entrez Gene: 397172 Pig Entrez Gene: 25029 Rat Entrez Gene: 527140 Cow Omim: 114190 Human SwissProt: Q16602 Human SwissProt: Q9R1W5 Mouse SwissProt: Q8WN93 Pig SwissProt: Q63118 Rat Unigene: 470882 Human Unigene: 11202 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
降钙素基因相关肽1型受体抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学 信号转导 G蛋白偶联受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid