巨噬细胞特异性凝集素抗体
规格：1mg/1ml
英文名： MMGL/Macrophage specific lectin
别名： carbohydrate-binding protein 35; CBP35; GAL3; galactose-specific lectin 3; GALBP; IgE-binding protein; laminin-binding protein; lectin galactoside-binding soluble 3 (galectin 3); LGALS2; MAC-2 antigen
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MMGL/Mac
交叉反应：Mouse,
细胞定位：细胞膜
巨噬细胞特异性凝集素抗体产品介绍：background: The antigen is found on the surface of connective tissue macrophages and their precursor cells in bone marrow. Macrophage cell lines (J774-1.6, RAW309Cr.1, WR19M.1) corresponding to mature macrophages express high levels of the antigen. Function: Recognizes terminal galactose and N-acetylgalactosamine units. May participate in the interaction between tumoricidal macrophages and tumor cells. Plays a role in the recruitment of inflammatory monocytes to adipose tissue in diet-induced 巨噬细胞特异性凝集素抗体obesity. Subunit: Homooligomer. Interacts with SIGLEC1, which may act as a counter-receptor for CLEC10A in lymph node. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Detected in lymph node in the subcapsular sinus, interfollicular regions, T and B-cell boundary and in the areas surrounding high endothelial venules (at protein level). Expressed on the surface of巨噬细胞特异性凝集素抗体 activated macrophages. Expressed in heart, lung, testis, skeletal muscle, spleen, brain, kidney and thymus. Expressed in P388, RAW 264.7 and M1 cell lines. Similarity: Contains 1 C-type lectin domain. Database links: Entrez Gene: 17312 Mouse SwissProt: P49300 Mouse Unigene: 252405 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产巨噬细胞特异性凝集素抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid