基质金属蛋白酶-15抗体
规格：1mg/1ml
英文名： MMP15
别名： Matrix metalloproteinase-15; MMP 15; MMP-15; MMP15; Matrix metallopeptidase 15 membrane inserted; Matrix metalloproteinase 15 ; Membrane type 2 Matrix Metalloproteinase; Membrane type matrix metallopr
分子量： 61kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MMP15
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞膜 细胞外基质
基质金属蛋白酶-15抗体产品介绍：background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than基质金属蛋白酶-15抗体 secreted. [provided by RefSeq, Jul 2008]. Function: Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. Subcellular Location: Membrane; Single-pass type I membrane protein; Extracellular side. Tissue Specificity: Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, 基质金属蛋白酶-15抗体kidney, lung, heart and skeletal muscle. Post-translational modifications: The precursor is cleaved by a furin endopeptidase (By similarity). Similarity: Belongs to the peptidase M10A family. Contains 4 hemopexin-like domains. Gene ID: 4324 Database links: Entrez Gene: 4324 Human Entrez Gene: 17388 Mouse Omim: 602261 Human SwissProt: P51511 Human SwissProt: O54732 Mouse Unigene: 80343 Human Unigene: 217116 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
基质金属蛋白酶-15抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid