ZC3H7A蛋白抗体
规格:1mg/1ml
英文名: ZC3H7A
别名: HSPC055; ZC3H7; ZC3HDC7; zinc finger CCCH type containing 7; zinc finger CCCH type containing 7A; zinc finger CCCH type domain containing 7; zinc finger protein AY163807.
分子量: 20kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZC3H7A
交叉反应:Human,
细胞定位:细胞核
ZC3H7A蛋白抗体产品介绍:background: ZC3H7A is a 971 amino acid protein that contains a C3H1-type zinc finger domain, three C3H1-type zinc fingers and three TPR repeats. Belonging to the ZC3H12 family, ZC3H7A localizes to the nucleus. Existing as two alternatively spliced isoforms, ZC3H7A is encoded by a gene located on human chromosome 16p13.13. Chromosome 16 makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation,ZC3H7A蛋白抗体 may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is aZC3H7A蛋白抗体 gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. Subcellular Location: Nuclear Database links: Entrez Gene: 29066 Human SwissProt: Q8IWR0 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ZC3H7A蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 结合蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid