核蛋白NHN1抗体
规格:1mg/1ml
英文名: ZC3H18/NHN1
别名: Conserved nuclear protein NHN1; NHN1; Nuclear protein NHN1; zc3h18; ZCH18_HUMAN; Zinc finger CCCH domain-containing protein 18.
分子量: 106kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZC3H18/N
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位:细胞核
核蛋白NHN1抗体产品介绍:background: NHN1 is a 953 amino acid nuclear protein that contains one C3H1-type zinc finger and exists as two alternatively spliced isoforms. The gene that encodes NHN1 contains more than 61,500 bases and maps to human chromosome 16q24.2. Encoding over 900 genes and consisting of approximately 90 million base pairs, chromosome 16 makes up nearly 3% of the human genome and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, when mutated, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. Alterations in the CREB gene and NOD2核蛋白NHN1抗体 gene, both of which are located on chromosome 16, results in Rubinstein-Taybi syndrome and Crohn's disease, respectively. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of核蛋白NHN1抗体 chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. Subcellular Location: Nucleus. Similarity: Contains 1 C3H1-type zinc finger. Gene ID: 124245 Database links: Entrez Gene: 124245 Human SwissProt: Q86VM9 Human Unigene: 93670 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核蛋白NHN1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 染色质和核信号 结合蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid