平滑肌蛋白LMOD2抗体
规格：1mg/1ml
英文名： LMOD2
别名： C-LMOD; Cardiac leiomodin; Leiomodin 2 (cardiac); Leiomodin-2; LMOD2; LMOD2_HUMAN.
分子量： 62kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LMOD2
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
细胞定位：细胞浆
平滑肌蛋白LMOD2抗体产品介绍：background: Members of the Leiomodin protein family are closely related to the tropomodulin family of actin filament pointed end-capping proteins. Leiomodins are actin-binding proteins that act as strong filament nucleators in muscle cells. Leiomodin 1 is highly expressed in a variety of tissues that contain smooth muscle, therefore it is also known as smooth muscle Leiomodin, or SM-Lmod. Also designated C-Lmod, Leiomodin 3 is found in several types of fetal tissue and is involved in tropomyosin binding. Leiomodin 2,平滑肌蛋白LMOD2抗体 also known as C-LMOD or LMOD2, is a 547 amino acid protein that is specifically expressed in heart and skeletal muscles. Leiomodin 2 binds to tropomyosin and may block the elongation and depolymerization of actin filaments at their pointed end. Leiomodin 2 is encoded by a gene that is located near the hypertrophic cardiomyopathy locus CMH6 on chromosome 7, suggesting that Leiomodin 2 may be involved in that disease process. Leiomodin 2 is expressed as three alternatively spliced variants. Function: May block the elongation and depolymerization of the actin filaments at the pointed end. Tissue Specificity: Specifically expressed in heart and skeletal muscles. Not expressed in other tissues. Similarity:平滑肌蛋白LMOD2抗体 Belongs to the tropomodulin family. Contains 1 WH2 domain. Gene ID: 442721 Database links: Entrez Gene: 442721 Human Entrez Gene: 93677 Mouse Omim: 608006 Human SwissProt: Q6P5Q4 Human SwissProt: Q3UHZ5 Mouse Unigene: 592260 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
平滑肌蛋白LMOD2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 发育生物学 信号转导 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid