LIN9蛋白抗体
规格:1mg/1ml
英文名: LIN9
别名: BARA; Beta subunit-associated regulator of apoptosis; Beta-subunit associated regulator of apoptosis; hLin-9; huLin-9; lin-9; lin9; LIN9_HUMAN; pRB-associated protein; Protein lin-9 homolog; TGS; TUDO
分子量: 62kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human LIN9
交叉反应:Human, Cynomolgus Monkey
细胞定位:细胞核
LIN9蛋白抗体产品介绍:background: This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] Function: Acts as a tumor suppressor. Inhibits DNA synthesis. LIN9蛋白抗体Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition. Subcellular Location: Nucleus > nucleoplasm. Found in perinucleolar structures. Associated with chromatin. Tissue Specificity: Expressed in thymus and testis. Similarity: Belongs to the lin-9 family. Gene ID: 286826 Database links: Entrez Gene: 286826 Human Entrez Gene:LIN9蛋白抗体 421316 Chicken Entrez Gene: 72568 Mouse Entrez Gene: 689523 Rat Entrez Gene: 323027 Zebrafish Entrez Gene: 560867 Zebrafish Omim: 609375 Human SwissProt: Q5TKA1 Human SwissProt: Q8C735 Mouse SwissProt: Q5RHQ8 Zebrafish Unigene: 120817 Human Unigene: 275044 Mouse Unigene: 214693 Rat Unigene: 76676 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
LIN9蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 细胞凋亡 细胞周期蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid