抑制素βB/Inhibin β B抗体
规格：1mg/1ml
英文名： Inhibin beta B
别名： MGC157939; Activin A; Activin AB alpha polypeptide; Activin AB; Activin AB beta polypeptide; Activin B; Activin beta A chain; Activin beta B chain; ActivinA; ActivinAB; ActivinB; EDF; Erythroid differ
分子量： 45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Inhibin
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep, Guinea Pig,
细胞定位：分泌型蛋白
抑制素βB/Inhibin β B抗体产品介绍：background: The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion,抑制素βB/Inhibin β B抗体 it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. 抑制素βB/Inhibin β B抗体[provided by RefSeq]. Subcellular Location: Secreted. Similarity: Belongs to the TGF-beta family. Gene ID: 3625 Database links: Entrez Gene: 3625 Human Entrez Gene: 16324 Mouse Entrez Gene: 25196 Rat Omim: 147390 Human SwissProt: P09529 Human SwissProt: Q04999 Mouse SwissProt: P17491 Rat Unigene: 1735 Human Unigene: 3092 Mouse Unigene: 35074 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 抑制素是转化生长因子TGFβ超级家族，主要由雌性动物卵巢颗粒细胞和雄性动物睾丸的Sertoli细胞分泌.研究表明,抑制素具有内抑制素βB/Inhibin β B抗体分泌和旁分泌物的作用:既可通过复杂的反馈机理,调节体液FSH水平。
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 生长因子和** 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid