线粒体LETM2抗体
规格：1mg/1ml
英文名： LETM2
别名： LETM1 and EF hand domain containing protein 2; LETM1 and EF-hand domain-containing protein 2; LETM1 domain containing protein LETM2 mitochondrial; LETM1 domain-containing protein LETM2; Letm2; LETM2_H
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LETM2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
线粒体LETM2抗体产品介绍：background: LETM2 is a 491 amino acid protein that is localized to the mitochondrial membrane and contains one LETM1 domain. Despite its name, LETM2, which is preferentially expressed in sperm and testis, does not contain any EF-hand domains. There are four isoforms of LETM2 that are produced as a result of alternative splicing events. A homolog of LETM2, LETM1 is thought to be involved in maintaining normal mitochondrial function and overall cell viability. Deletions in the gene encoding LETM1 线粒体LETM2抗体are associated with Wolf-Hirschhorn syndrome (WHS), a congenital syndrome characterized by a number of abnormalities, including mental retardation, seizures, heart defects, fused teeth, hearing loss, a webbed neck and renal abnormalities. The LETM2 gene is located on chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Subcellular Location: Mitochondrion inner membrane. Similarity: 线粒体LETM2抗体Contains 1 LETM1 domain. Gene ID: 137994 Database links: Entrez Gene: 137994 Human GenBank: NP_653253.1 Human SwissProt: Q2VYF4 Human Unigene: 696457 Human Unigene: 734005 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产线粒体LETM2抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 线粒体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid