8号染色体开放阅读框35抗体
规格：1mg/1ml
英文名： INTS10/C8orf35
别名： C8orf35; Chromosome 8 open reading frame 35; FLJ10569; INT10_HUMAN; INT10; Integrator complex subunit 10.
分子量： 82kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human INTS10/C
交叉反应：Human, Mouse, Rat, Pig, Cow, Cynomolgus Monkey, Rhesus monkey
细胞定位：细胞核
8号染色体开放阅读框35抗体产品介绍：background: INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008] Function: INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit and mediates 3-prime end processing of small nuclear RNAs U1. Subunit: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3,8号染色体开放阅读框35抗体 INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12. Interacts with POLR2A. Subcellular Location: Nuclear Similarity: Belongs to the Integrator subunit 10 family. Gene ID: 55174 Database links: Entrez Gene: 55174 Human Entrez Gene: 422489 Chicken Entrez Gene: 534094 Cow Entrez Gene: 70885 Mouse Entrez Gene: 290679 Rat Entrez Gene: 705240 Rhesus monkey Omim:8号染色体开放阅读框35抗体 611353 Human SwissProt: Q5ZLS8 Chicken SwissProt: Q4R7B1 Cynomolgus Monkey SwissProt: Q9NVR2 Human SwissProt: Q8K2A7 Mouse Unigene: 512627 Human Unigene: 252421 Mouse Unigene: 2385 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
8号染色体开放阅读框35抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid