胃内在因子抗体
规格:1mg/1ml
英文名: Intrinsic Factor
别名: Gastric Intrinsic Factor; Gastric intrinsic factor (vitamin B synthesis); GIF; IF; IFMH; INF; Intrinsic factor; TCM3; TCN3.
分子量: 43kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Intrinsi
交叉反应:Human, Mouse, Rat,
细胞定位:分泌型蛋白
胃内在因子抗体产品介绍:background: This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia. [provided by RefSeq, Jul 2008] Function: Intrinsic factor promotes absorption of the essential vitamin Cobalamin (Cbl) in the ileum by specific receptor mediated endocytosis. Defects in the gene GIF are胃内在因子抗体 the cause of hereditary intrinsic factor deficiency (IFD) also called congenital pernicious anemia. IFD is an autosomal recessive disorder characterized by megaloblastic anemia. Subcellular Location: Secreted Tissue Specificity: Gastric mucosa. DISEASE: Hereditary intrinsic factor deficiency (IFD) Similarity: Belongs to the eukaryotic cobalamin transport proteinsfamily. Gene ID: 2694 Database links: Entrez Gene: 2694 胃内在因子抗体Human Entrez Gene: 14603 Mouse Entrez Gene: 29319 Rat Omim: 609342 Human SwissProt: P27352 Human SwissProt: P52787 Mouse SwissProt: P17267 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产胃内在因子抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid