MPV17L蛋白抗体
规格:1mg/1ml
英文名: MPV17L
别名: FLJ39599; M LP homolog; M LPH; MGC70356; MLPH1; MLPH2; MPV 17L; Mpv17 like protein type 1; Mpv17 like protein type 2; MPV17 mitochondrial membrane protein like; MPV17L1.
分子量: 22kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MPV17L
交叉反应:Human, Mouse,
细胞定位:
MPV17L蛋白抗体产品介绍:background: MPV17L is a 196 amino acid multi-pass membrane protein belonging to the peroxisomal membrane protein PXMP2/4 family. M-LPS (also known as M-LPH1) and M-LPL (also known as M-LPH2) are alternatively spliced isoforms of MPV17L and are ubiquitously expressed in human tissues, however only M-LPS exists at the protein level and mainly resides in kidney. MPV17L may be involved in protecting against mitochondrial oxidative stress and apoptosis, and participates in reactive oxygen species (ROS) metabolism by up- or down-regulating genes of antioxidant enzymes. MPV17L may play a role in the development of early-onset glomerulosclerosis, which is MPV17L蛋白抗体the hardening or formation of scar tissue of the glomerulus in the kidney. The gene encoding MPV17L maps to human chromosome 16p13.11. Function: MPV17L Isoform 1 participates in reactive oxygen species metablism by up- or down-regulation of the genes of antioxidant enzymes. Subcellular Location: Isoform 1: Peroxisome membrane; Multi-pass membrane protein. Tissue Specificity: Isoform 1 is detected in MPV17L蛋白抗体the kidney (at protein level). Isoform 1 and isoform 2 are expressed in the kidney, heart, liver, lung, pancreas and skeletal muscle. Similarity: Belongs to the peroxisomal membrane protein PXMP2/4 family. Gene ID: 255027 Database links: Entrez Gene: 255027 Human SwissProt: Q2QL34 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MPV17L蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 细胞凋亡
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid