异质核糖核蛋白A0抗体
规格：1mg/1ml
英文名： hnRNP A0
别名： HNRNPA0; Heterogeneous nuclear ribonucleoprotein A0; hnRNA binding protein; hnRNP A0; HNRNPA0; ROA0_HUMAN.
分子量： 31kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human hnRNP A0
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Chimpanzee, Cynomolgus Monkey, Rhesus monkey, Gorilla, Marmoset (common)
细胞定位：细胞核
异质核糖核蛋白A0抗体产品介绍：background: Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins and their complexes are the major constituents of the spliceosome. The majority of hnRNP protein components are localized to the nucleus; however, some shuttle between the nucleus and the cytoplasm. hnRNP I, also designated polypyrimidine tract-binding protein (PTB), and its异质核糖核蛋白A0抗体 homolog hnRNP L, bind to the 3' end of introns to modulate alternative splicing mechanisms of pre-mRNAs in normal cells and the translation of sev-eral viruses, including hepatitis C virus (HCV). The human hnRNP I gene maps to chromosome 19p13.3 and encodes a protein that is localized in the nucleoplasm. hnRNP L, like hnRNP I, is also localized in the nucleoplasm. Function: This protein is a component of ribonucleosomes.异质核糖核蛋白A0抗体 Subcellular Location: Nucleus. Component of ribonucleosomes. Post-translational modifications: Arg-291 is dimethylated, probably to asymmetric dimethylarginine. Similarity: Contains 2 RRM (RNA recognition motif) domains. Database links: Entrez Gene: 416302 Chicken Entrez Gene: 745876 Chimpanzee Entrez Gene: 540311 Cow Entrez Gene: 481524 Dog Entrez Gene: 10949 Human Entrez Gene: 77134 Mouse Entrez Gene: 498696 Rat Omim: 609409 Human SwissProt: Q13151 Human SwissProt: Q9CX86 Mouse Unigene: 645902 Human Unigene: 96996 Human Unigene: 490274 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
异质核糖核蛋白A0抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit